General Information

    • DRAMP ID

    • DRAMP03733

    • Peptide Name

    • Lysozyme (Arthropods, animals)

    • Source

    • Tityus stigmurus (Brazilian scorpion)

    • Family

    • Belongs to the glycosyl hydrolase 22 family

    • Gene

    • Not found

    • Sequence

    • SIYERCELARELINR

    • Sequence Length

    • 15

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03733 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03733.

Physicochemical Information

    • Formula

    • C79H133N25O25S

    • Absent Amino Acids

    • DFGHKMPQTVW

    • Common Amino Acids

    • ER

    • Mass

    • 1865.14

    • PI

    • 5.95

    • Basic Residues

    • 3

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 5

    • Net Charge

    • 0

    • Boman Index

    • -52.6

    • Hydrophobicity

    • -0.58

    • Aliphatic Index

    • 110.67

    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 106.43

    • Polar Residues

    • 4

DRAMP03733

Comments Information

    • Function

    • Lysozymes have primarily a bacteriolytic Function

    • Catalytic activity

    • Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

    • Tissue specificity

    • Expressed by the venom gland.

Literature Information

  • ·Literature 1

    • Title

    • Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species.

    • Reference

    • Comp Biochem Physiol C Toxicol Pharmacol. 2007 Jul-Aug;146(1-2):147-157.

    • Author

    • Batista C.V.F, Roman-Gonzalez S.A, Salas-Castillo S.P, Zamudio F.Z, Gomez-Lagunas F, Possani L.D.