• DRAMP ID

    • DRAMP03742
    • Peptide Name

    • Ponericin-W-like 32.2 (Arthropods, animals)
    • Source

    • Lychas mucronatus (Chinese swimming scorpion)
    • Family

    • Belongs to the ponericin-W family
    • Gene

    • Not found
    • Sequence

    • IFGSLFSLGSKLLPTVFKLFSRKKQ
    • Sequence Length

    • 25
    • Protein Existence

    • Transcript level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Insecticidal
    • Target Organism

    • [Swiss_Prot Entry P0CI92]Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae
    • Hemolytic Activity

      • [Swiss_Prot Entry P0CI92]has hemolytic activities
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03742 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03742.
    • Formula

    • C137H221N33O32
    • Absent Amino Acids

    • ACDEHMNWY
    • Common Amino Acids

    • L
    • Mass

    • 2842.46
    • PI

    • 11.33
    • Basic Residues

    • 5
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 11
    • Net Charge

    • +5
    • Boman Index

    • -11.47
    • Hydrophobicity

    • 0.36
    • Aliphatic Index

    • 105.2
    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 7

DRAMP03742

DRAMP03742 chydropathy plot
    • Function

    • Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae. Has insecticidal and hemolytic activities (By similarity).
    • Tissue specificity

    • Expressed by the venom gland.
  • ·Literature 1
    • Title

    • Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components.
    • Reference

    • BMC Genomics. 2010 Jul 28;11:452.
    • Author

    • Ruiming Z, Yibao M, Yawen H, Zhiyong D, Yingliang W, Zhijian C, Wenxin L.