General Information

    • DRAMP ID

    • DRAMP03745

    • Peptide Name

    • Peptide BmKn1 (Biologically active peptide 4; NDBP-5.1; Arthropods, animals)

    • Source

    • Mesobuthus martensii (Buthus martensii)

    • Family

    • Belongs to the scorpion NDBP 5 family

    • Gene

    • Kn1

    • Sequence

    • FIGAVAGLLSKIF

    • Sequence Length

    • 13

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03745 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03745.

Physicochemical Information

    • Formula

    • C66H106N14O15

    • Absent Amino Acids

    • CDEHMNPQRTWY

    • Common Amino Acids

    • AFGIL

    • Mass

    • 1335.65

    • PI

    • 8.75

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +1

    • Boman Index

    • 26.23

    • Hydrophobicity

    • 1.885

    • Aliphatic Index

    • 157.69

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP03745

Comments Information

    • Function

    • Antibacterial peptide (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Precursor of a novel scorpion venom peptide (BmKn1) with no disulfide bridge from Buthus martensii Karsch.

    • Reference

    • IUBMB Life. 2001 Feb;51(2):117-120.

    • Author

    • Zeng XC, Li WX, Wang SX, Zhu SY, Luo F.
  • ·Literature 2

    • Title

    • A full-length cDNA encoding a putative active peptide, peptide 4, from Buthus martensii Karsch.

    • Reference

    • Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.

    • Author

    • Li WX, Zhu SY.