• DRAMP ID

    • DRAMP03790
    • Peptide Name

    • ABF-2 (nematodes, animals)
    • Source

    • Caenorhabditis elegans
    • Family

    • Not found
    • Gene

    • abf-2
    • Sequence

    • DIDFSTCARMDVPILKKAAQGLCITSCSMQNCGTGSCKKRSGRPTCVCYRCANGGGDIPLGALIKRG
    • Sequence Length

    • 67
    • Protein Existence

    • Predicted
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • Gram-positive bacteria: Bacillus subtilis IFO3134 (BC50=0.09 µM), Kocuria varians MAFF118076 (BC50=0.008 µM), Staphylococcus aureus ATCC6538P (BC50=0.005 µM);
      • Gram-negative bacteria: Agrobacterium tumefaciens MAFF1001 (BC50=0.05 µM), Bdellovibrio bacteriovorus MAFF106101 (BC50=0.06 µM), Klebsiella pneumoniae MAFF519002 (BC50=0.9 µM), Escherichia coli JM109 (BC50>15 µM).
      • Fungi: Candida krusei MAFF114085 (BC50=0.3 µM), Debaryomyces hansenii MAFF113836 (BC50>15 µM), Kluyveromyces thermotolerans MAFF113848 (BC50=0.3 µM), Paeonia anomala MAFF113717 (BC50=0.08 µM), Saccharomyces cerevisiae MAFF113011 (BC50=0.6 µM), Torulaspora delbrueckiiMAFF113811 (BC50>15 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03790 helical wheel diagram
    • Predicted Structure

    • There is no predicted structure for DRAMP03790.
    • Formula

    • C289H489N91O90S10
    • Absent Amino Acids

    • EHW
    • Common Amino Acids

    • GC
    • Mass

    • 6999.22
    • PI

    • 9.08
    • Basic Residues

    • 10
    • Acidic Residues

    • 4
    • Hydrophobic Residues

    • 17
    • Net Charge

    • +6
    • Boman Index

    • -101.22
    • Hydrophobicity

    • -0.072
    • Aliphatic Index

    • 68.51
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1990
    • Absorbance 280nm

    • 30.15
    • Polar Residues

    • 29

DRAMP03790

DRAMP03790 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans.
    • Reference

    • Biochem J. 2002 Jan 15;361(Pt 2):221-230.
    • Author

    • Kato Y, Aizawa T, Hoshino H, Kawano K, Nitta K, Zhang H.