General Information

    • DRAMP ID

    • DRAMP03794

    • Peptide Name

    • Caenacin-4 (Gly-rich, Tyr-rich; CNC-4, nematode, invertebrate, animals)

    • Source

    • Caenorhabditis elegans

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • QWGYGPYGGYGGGYPGMYGGYGMRPYGMYGGYGMGMYRPGLLGMLIGK

    • Sequence Length

    • 48

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03794 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03794.

Physicochemical Information

    • Formula

    • C236H329N57O60S6

    • Absent Amino Acids

    • ACDEFHNSTV

    • Common Amino Acids

    • G

    • Mass

    • 5116.91

    • PI

    • 9.35

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +3

    • Boman Index

    • 11.64

    • Hydrophobicity

    • -0.354

    • Aliphatic Index

    • 32.5

    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 20400

    • Absorbance 280nm

    • 434.04

    • Polar Residues

    • 29

DRAMP03794

DRAMP03794 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

    • Reference

    • Nat Immunol. 2004 May;5(5):488-494.

    • Author

    • Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ.