• DRAMP ID

    • DRAMP03849
    • Peptide Name

    • ETD156 (Mutant of ARD1; Heliomicin analogs)
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • DKLIGSCVWLAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCET
    • Sequence Length

    • 44
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Synthetic
    • Biological Activity

    • Antimicrobial, Antifungal
    • Target Organism

      • Fungi: Candida albicans IHEM 8060 (MIC50=3.125 µg/ml), Aspergillus fumigatus GASP4707 (MIC50=25 µg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03849 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03849.
    • Formula

    • C206H314N62O63S6
    • Absent Amino Acids

    • MPQ
    • Common Amino Acids

    • C
    • Mass

    • 4859.5
    • PI

    • 8.32
    • Basic Residues

    • 6
    • Acidic Residues

    • 3
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +3
    • Boman Index

    • -69.98
    • Hydrophobicity

    • -0.323
    • Aliphatic Index

    • 53.18
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 14355
    • Absorbance 280nm

    • 333.84
    • Polar Residues

    • 23

DRAMP03849

DRAMP03849 chydropathy plot
    • Function

    • Possess antifungal activity.
  • ·Literature 1
    • Title

    • Lead optimization of antifungal peptides with 3D NMR structures analysis.
    • Reference

    • Protein Sci. 2004 Mar;13(3):703-713.
    • Author

    • Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL.