• DRAMP ID

    • DRAMP03871
    • Peptide Name

    • cLf 20-29 (fragment of caprine lalctoferricin, residues 20-29)
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • YQWQRRMRKL
    • Sequence Length

    • 10
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Synthetic
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=308 µM), Escherichia coli (wild strain) (MIC>300 µM);
      • Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=308 µM), Enterococcus faecalis ATCC 29212 (MIC>300 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03871 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03871.
    • Formula

    • C65H105N23O14S
    • Absent Amino Acids

    • ACDEFGHINPSTV
    • Common Amino Acids

    • R
    • Mass

    • 1464.75
    • PI

    • 11.72
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 2
    • Net Charge

    • +4
    • Boman Index

    • -51.93
    • Hydrophobicity

    • -2.09
    • Aliphatic Index

    • 39
    • Half Life

      • Mammalian:2.8 hour
      • Yeast:10 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 6990
    • Absorbance 280nm

    • 776.67
    • Polar Residues

    • 1

DRAMP03871

    • Function

    • Shows antibacterial activity against both Gram-positive and Gram-negative bacteria.
  • ·Literature 1
    • Title

    • Antibacterial activity of short hydrophobic and basic-rich peptides.
    • Reference

    • Am J Vet Res. 2003 Sep;64(9):1088-1092.
    • Author

    • Chen PW, Shyu CL, Mao FC.