• • DRAMP ID

  • DRAMP03876

• • Peptide Name

  • LFB-RW (derivative of bovine lactoferrin with residues substitution)

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • RRWWWRWRRW

• • Sequence Length

  • 10

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=15 µM), Escherichia coli (wild strain) (MIC=5.63 µM);
    • Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=7.5 µM), Enterococcus faecalis ATCC 29212 (MIC=11.25 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP03876_predicted_structure.pdb to download.

DRAMP03876

• • Function

  • Shows antibacterial activity against both Gram-positive and Gram-negative bacteria.

• ·Literature 1

• • Title

  • Antibacterial activity of short hydrophobic and basic-rich peptides.

• • Pubmed ID

  • 13677384

• • Reference

  • Am J Vet Res. 2003 Sep;64(9):1088-1092.

• • Author

  • Chen PW, Shyu CL, Mao FC.