• • DRAMP ID

  • DRAMP03912

• • Peptide Name

  • LFM R1,9 W8 Y13 (LFM W8 derivative with residues substitution)

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • RKCLRWQWRMRKYGG

• • Sequence Length

  • 15

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacterium: Escherichia coli (MIC=10 µM);
    • Gram-positive bacterium: Staphylococcus aureus (MIC=12 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP03912_predicted_structure.pdb to download.

DRAMP03912

• • Function

  • Has antibacterial activity against the Gram-positive bacterium S. aureus and the Gram-negative bacteria E. coli.

• ·Literature 1

• • Title

  • Increased antibacterial activity of 15-residue murine lactoferricin derivatives.

• • Pubmed ID

  • 11168896

• • Reference

  • J Pept Res. 2001 Feb;57(2):127-139.

• • Author

  • Strøm MB, Rekdal O, Stensen W, Svendsen JS.