General Information

    • DRAMP ID

    • DRAMP03919

    • Peptide Name

    • (RW)5

    • Source

    • Synthetic construct (De novo design)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RWRWRWRWRW

    • Sequence Length

    • 10

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Fusarium solani, Fusarium oxysporum.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03919 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03919.

Physicochemical Information

    • Formula

    • C85H112N30O11

    • Absent Amino Acids

    • ACDEFGHIKLMNPQSTV

    • Common Amino Acids

    • RW

    • Mass

    • 1730.02

    • PI

    • 12.6

    • Basic Residues

    • 5

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +5

    • Boman Index

    • -62.95

    • Hydrophobicity

    • -2.7

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 27500

    • Absorbance 280nm

    • 3055.56

    • Polar Residues

    • 0

DRAMP03919

Comments Information

    • Function

    • Possess antifungal activity.

Literature Information

  • ·Literature 1

    • Title

    • Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum.

    • Reference

    • Int J Mol Sci. 2012; 13(11): 15042-15053.

    • Author

    • Gopal R, Na H, Seo CH, Park Y.