General Information

    • DRAMP ID

    • DRAMP03940

    • Peptide Name

    • Peptide 4 (Trp- and Arg-rich; derivative of Tritrpticin)

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FPWWWPF

    • Sequence Length

    • 7

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Rich

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03940 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03940.

Physicochemical Information

    • Formula

    • C61H64N10O8

    • Absent Amino Acids

    • ACDEGHIKLMNQRSTVY

    • Common Amino Acids

    • W

    • Mass

    • 1065.24

    • PI

    • 5.52

    • Basic Residues

    • 0

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • 0

    • Boman Index

    • 12.95

    • Hydrophobicity

    • -0.043

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 16500

    • Absorbance 280nm

    • 2750

    • Polar Residues

    • 0

DRAMP03940

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial activity of a 13 amino acid tryptophan-rich peptide derived from a putative porcine precursor protein of a novel family of antibacterial peptides.

    • Reference

    • FEBS Lett. 1996 Jul 15;390(1):95-98.

    • Author

    • Lawyer C, Pai S, Watabe M, Borgia P, Mashimo T, Eagleton L, Watabe K.