• • DRAMP ID

  • DRAMP03948

• • Peptide Name

  • Del 1 (Ranalexin analog)

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • LGGLIKIVPAMICAVTKKC

• • Sequence Length

  • 19

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-positive bacterium: Staphylococcus aureus (MIC=256 µg/ml);
    • Gram-negative bacteria: Escherichia coli (MIC=256 µg/ml), Pseudomonas aeruginosa (MIC>256 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP03948_predicted_structure.pdb to download.

DRAMP03948

• • Function

  • Has antibacterial activiy against Gram-negative and Gram-positive bacteria.

• ·Literature 1

• • Title

  • Ranalexin. A novel antimicrobial peptide from bullfrog (Rana catesbeiana) skin, structurally related to the bacterial antibiotic, polymyxin.

• • Pubmed ID

  • 8144672

• • Reference

  • J Biol Chem. 1994 Apr 8;269(14):10849-10855.

• • Author

  • Clark DP, Durell S, Maloy WL, Zasloff M.