General Information
-
DRAMP ID
- DRAMP03954
-
Peptide Name
- Rat CGA7–57
-
Source
- Synthetic construct
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- MTKGDTKVMKCVLEVISDSLSKPSPMPVSPECLETLQGDERILSVLRHQNL
-
Sequence Length
- 51
-
UniProt Entry
- No entry found
-
Protein Existence
- Synthetic
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
-
- Fungi: Neurospora crassa (MIC=10 µg/ml), Alternaria brassicicola (MIC=20 µg/ml), Nectria haematococca (MIC=10 µg/ml), Fusarium culmorum (MIC=20 µg/ml).
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03954.
Physicochemical Information
-
Formula
- C242H412N66O78S5
Absent Amino Acids
- AFWY
Common Amino Acids
- LS
Mass
- 5654.63
PI
- 5.62
Basic Residues
- 7
Acidic Residues
- 7
Hydrophobic Residues
- 14
Net Charge
- 0
-
Boman Index
- -79.96
Hydrophobicity
- -0.188
Aliphatic Index
- 97.25
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 125
Absorbance 280nm
- 2.5
Polar Residues
- 14
DRAMP03954
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A.
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Pubmed ID
- 10753865
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Reference
- J Biol Chem. 2000 Apr 14;275(15):10745-10753.
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Author
- Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH.