General Information

    • DRAMP ID

    • DRAMP04008

    • Peptide Name

    • Plasticin-C1 (PTC-C1; DRP-AC-1; frogs, amphibians, animals)

    • Source

    • Agalychnis callidryas

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GLLSGILNTAGGLLGNLIGSLSN

    • Sequence Length

    • 23

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04008 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04008.

Physicochemical Information

    • Formula

    • C94H164N26O31

    • Absent Amino Acids

    • CDEFHKMPQRVWY

    • Common Amino Acids

    • L

    • Mass

    • 2154.49

    • PI

    • 5.52

    • Basic Residues

    • 0

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 10

    • Net Charge

    • 0

    • Boman Index

    • 19.04

    • Hydrophobicity

    • 0.93

    • Aliphatic Index

    • 156.96

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 13

DRAMP04008

DRAMP04008 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain.

    • Reference

    • Eur J Biochem. 2003 May;270(9):2068-2081.

    • Author

    • Vanhoye D, Bruston F, Nicolas P, Amiche M.