• DRAMP ID

    • DRAMP04044
    • Peptide Name

    • Immobilized peptid E12LLK
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • LKKLLKKLKKLL
    • Sequence Length

    • 12
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Synthetic
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;
      • Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.
      • Yeast: Candida albicans ATCC 10231.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP04044 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP04044.
    • Formula

    • C72H140N18O13
    • Absent Amino Acids

    • ACDEFGHIMNPQRSTVW
    • Common Amino Acids

    • KL
    • Mass

    • 1466.02
    • PI

    • 10.7
    • Basic Residues

    • 6
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 6
    • Net Charge

    • +6
    • Boman Index

    • -3.78
    • Hydrophobicity

    • -0.05
    • Aliphatic Index

    • 195
    • Half Life

      • Mammalian:5.5 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 0

DRAMP04044

    • Function

    • Has antibacterial activiy against Gram-negative and Gram-positive bacteria.
  • ·Literature 1
    • Title

    • Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
    • Reference

    • Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.
    • Author

    • Haynie SL, Crum GA, Doele BA.