• • DRAMP ID

  • DRAMP04101

• • Peptide Name

  • 3IQ4

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • KNVNSIVKIQAFFRARKAQDDYR

• • Sequence Length

  • 23

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-negative bacterium: Escherichia coli (MIC=3.5 µM);
    • Gram-positive bacterium: Staphylococcus aureus (MIC=4.6 µM).
    • Yeast: Candida albicans (MIC=30 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP04101_predicted_structure.pdb to download.

DRAMP04101

• • Function

  • Displays antimicrobial activity against bacteria and yeast C. albicans.

• ·Literature 1

• • Title

  • IQ-motif peptides as novel anti-microbial agents.

• • Pubmed ID

  • 23238369

• • Reference

  • Biochimie. 2013 Apr;95(4):875-880.

• • Author

  • McLean DT, Lundy FT, Timson DJ.