• • DRAMP ID

  • DRAMP04135

• • Peptide Name

  • LK2(6)AN(2L) (Temporin-1CEa analog peptide)

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • FVKLKKILNIILSIFKK

• • Sequence Length

  • 17

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Anti-cancer

• • Target Organism

  • • Cancer cell lines: MCF-7 (IC50=11 µM), MDA-MB-231 (IC50=41.55 µM), Bcap-37 (IC50=9.39 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP04135.

DRAMP04135

• • Function

  • Has anticancer activity.

• ·Literature 1

• • Title

  • Design of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa.

• • Pubmed ID

  • 23609760

• • Reference

  • Arch Pharm Res. 2013 Apr 23.

• • Author

  • Yang QZ, Wang C, Lang L, Zhou Y, Wang H, Shang DJ.