General Information

    • DRAMP ID

    • DRAMP04154

    • Peptide Name

    • RL4 (homologue of Pc-CATH1)

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FWPVVIRTVVAGYNLYRAIKKK

    • Sequence Length

    • 22

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04154 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04154.

Physicochemical Information

    • Formula

    • C127H201N33O27

    • Absent Amino Acids

    • CDEHMQS

    • Common Amino Acids

    • V

    • Mass

    • 2622.2

    • PI

    • 10.56

    • Basic Residues

    • 5

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +5

    • Boman Index

    • -15.19

    • Hydrophobicity

    • 0.255

    • Aliphatic Index

    • 115

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 8480

    • Absorbance 280nm

    • 403.81

    • Polar Residues

    • 5

DRAMP04154

DRAMP04154 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.

    • Reference

    • Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.

    • Author

    • Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai.