General Information
-
DRAMP ID
- DRAMP04158
-
Peptide Name
- RL8 (homologue of Pc-CATH1)
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Source
- Synthetic construct
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- VIRTVVAGYNLYRAIKKK
-
Sequence Length
- 18
-
UniProt Entry
- No entry found
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Protein Existence
- Synthetic
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP04158.
Physicochemical Information
-
Formula
- C97H166N28O23
Absent Amino Acids
- CDEFHMPQSW
Common Amino Acids
- KV
Mass
- 2092.56
PI
- 10.56
Basic Residues
- 5
Acidic Residues
- 0
Hydrophobic Residues
- 8
Net Charge
- +5
-
Boman Index
- -24.54
Hydrophobicity
- 0.061
Aliphatic Index
- 124.44
Half Life
-
- Mammalian:100 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 2980
Absorbance 280nm
- 175.29
Polar Residues
- 5
DRAMP04158
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
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Pubmed ID
- PubMed ID is not available
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Reference
- Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.
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Author
- Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai.