General Information

    • DRAMP ID

    • DRAMP04197

    • Peptide Name

    • Penetratin

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RQIKIWFQNRRMKWKK

    • Sequence Length

    • 16

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04197 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04197.

Physicochemical Information

    • Formula

    • C104H168N34O20S

    • Absent Amino Acids

    • ACDEGHLPSTVY

    • Common Amino Acids

    • K

    • Mass

    • 2246.75

    • PI

    • 12.31

    • Basic Residues

    • 7

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +7

    • Boman Index

    • -64.85

    • Hydrophobicity

    • -1.731

    • Aliphatic Index

    • 48.75

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 11000

    • Absorbance 280nm

    • 733.33

    • Polar Residues

    • 1

DRAMP04197

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial and cell-penetrating properties of penetratin analogs: Effect of sequence and secondary structure.

    • Reference

    • Biochim Biophys Acta. 2013 Feb;1828(2):223-232.

    • Author

    • Bahnsen JS, Franzyk H, Sandberg-Schaal A, Nielsen HM.