General Information

    • DRAMP ID

    • DRAMP04218

    • Peptide Name

    • Lys-a1

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • KIFGAIWPLALGALKNLIK

    • Sequence Length

    • 19

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04218 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04218.

Physicochemical Information

    • Formula

    • C102H168N24O21

    • Absent Amino Acids

    • CDEHMQRSTVY

    • Common Amino Acids

    • L

    • Mass

    • 2066.6

    • PI

    • 10.3

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +3

    • Boman Index

    • 23.77

    • Hydrophobicity

    • 0.968

    • Aliphatic Index

    • 159.47

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 305.56

    • Polar Residues

    • 3

DRAMP04218

DRAMP04218 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial activity of the synthetic peptide Lys-a1 against oral streptococci.

    • Reference

    • Peptides. 2013 Apr;42:78-83.

    • Author

    • da Silva BR, de Freitas VA, Carneiro VA, Arruda FV, Lorenzón EN, de Aguiar AS, Cilli EM, Cavada BS, Teixeira EH.