General Information

    • DRAMP ID

    • DRAMP04225

    • Peptide Name

    • Dros-Pyrr-Dros

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GKPRPYLPRPTSHPRPIRV

    • Sequence Length

    • 19

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04225 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04225.

Physicochemical Information

    • Formula

    • C101H166N34O23

    • Absent Amino Acids

    • ACDEFMNQW

    • Common Amino Acids

    • P

    • Mass

    • 2224.64

    • PI

    • 12.01

    • Basic Residues

    • 6

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 3

    • Net Charge

    • +6

    • Boman Index

    • -61.18

    • Hydrophobicity

    • -1.337

    • Aliphatic Index

    • 56.32

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 82.78

    • Polar Residues

    • 4

DRAMP04225

DRAMP04225 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • The efficacy of the antibacterial peptide, pyrrhocoricin, is finely regulated by its amino acid residues and active domains.

    • Reference

    • Letters in Peptide Science. 2001;8(3-5):201-209.

    • Author

    • Bencivengo AM, Cudic M, Hoffmann R, Jr LO.