General Information

    • DRAMP ID

    • DRAMP04228

    • Peptide Name

    • PGP

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GRFRRLGRKFKKLFKKYGP

    • Sequence Length

    • 19

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04228 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04228.

Physicochemical Information

    • Formula

    • C113H184N36O21

    • Absent Amino Acids

    • ACDEHIMNQSTVW

    • Common Amino Acids

    • K

    • Mass

    • 2382.93

    • PI

    • 12.02

    • Basic Residues

    • 9

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +9

    • Boman Index

    • -65.97

    • Hydrophobicity

    • -1.347

    • Aliphatic Index

    • 41.05

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 82.78

    • Polar Residues

    • 4

DRAMP04228

DRAMP04228 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity.

    • Reference

    • Eur J Biochem. 1997 Dec 1;250(2):549-558.

    • Author

    • Tossi A, Tarantino C, Romeo D.