• • DRAMP ID

  • DRAMP04243

• • Peptide Name

  • Synthetic 4

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • RLKLLLLRLK

• • Sequence Length

  • 10

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-positive bacteria: Staphylococcus aureus (MIC=2 µg/ml), S. aureus (MRSA) (MIC>35 µg/ml).
    • Gram-negative bacterium: Escherichia coli (MIC=20 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP04243_predicted_structure.pdb to download.

DRAMP04243

• • Function

  • Has antibacterial activity against the Gram-positive and Gram-negative bacteria.

• ·Literature 1

• • Title

  • Novel synthetic antimicrobial peptides effective against methicillin-resistant Staphylococcus aureus.

• • Pubmed ID

  • 8093007

• • Reference

  • Biochem J. 1994 Sep 1;302 ( Pt 2):535-538.

• • Author

  • Alvarez-Bravo J, Kurata S, Natori S.