General Information

    • DRAMP ID

    • DRAMP04246

    • Peptide Name

    • Dhvar4

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • KRLFKKLLFSLRKY

    • Sequence Length

    • 14

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04246 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04246.

Physicochemical Information

    • Formula

    • C90H150N24O17

    • Absent Amino Acids

    • ACDEGHIMNPQTVW

    • Common Amino Acids

    • KL

    • Mass

    • 1840.33

    • PI

    • 11.22

    • Basic Residues

    • 6

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 6

    • Net Charge

    • +6

    • Boman Index

    • -29.94

    • Hydrophobicity

    • -0.421

    • Aliphatic Index

    • 111.43

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 114.62

    • Polar Residues

    • 2

DRAMP04246

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Cationic amphipathic peptides, derived from bovine and human lactoferrins, with antimicrobial activity against oral pathogens.

    • Reference

    • FEMS Microbiol Lett. 1999 Oct 15;179(2):217-222.

    • Author

    • Groenink J, Walgreen-Weterings E, van 't Hof W, Veerman EC, Nieuw Amerongen AV.