• • DRAMP ID

  • DRAMP04279

• • Peptide Name

  • CP11CN

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • ILKKWPWWPWRRK

• • Sequence Length

  • 13

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+

• • Target Organism

  • • Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=16 µg/ml), S. aureus SAP0017 MRSA (MIC=16 µg/ml), Staphylococcus haemolyticus Clinical isolate (MIC=2 µg/ml), S. haemolyticus Vancomycin-resistant isolate (MIC=1 µg/ml), Staphylococcus epidermidis Clinical isolate (MIC=8 µg/ml), Enterococcus faecalis ATCC 29212 (MIC>64 µg/ml), Listeria monocytogenes NCTC 7973 (MIC=16 µg/ml), Streptococcus pyogenes ATCC 19615 (MIC=8 µg/ml), Corynebacterium xerosis Lab strain (MIC=0.5 µg/ml).(Ref.2)

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP04279.

DRAMP04279

• • Chemical modification

  • C-terminal amidation.

• ·Literature 1

• • Title

  • Salt-resistant alpha-helical cationic antimicrobial peptides.

• • Pubmed ID

  • 11294848

• • Reference

  • Antimicrob. Agents Chemother. 1999,43:1542-1548.

• • Author

  • Friedrich, C, M. G. Scott, N. Karunaratne, H. Yan, and R. E. Hancock.