• • DRAMP ID

  • DRAMP04282

• • Peptide Name

  • CM3

• • Source

  • Synthetic construct

• • Family

  • Derived from the peptide CP26, CP29, CEME and CEMA

• • Gene

  • Not found

• • Sequence

  • KWKKFIKSLTKSAAKTVVKTAKKPLIV

• • Sequence Length

  • 27

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram-

• • Target Organism

  • • Gram-negative bacteria: Escherichia coli (MIC=1 μg/ml), Salmonella typhimurium (MIC=3 μg/ml), Pseudomonas aeruginosa K799 (MIC=4 μg/ml), Pseudomonas aeruginosa Z61 (MIC=3 μg/ml), Pseudomonas aeruginosa H744 (MIC=2 μg/ml), Pseudomonas aeruginosa H374 (MIC=2 μg/ml), Pseudomonas aeruginosa H547 (MIC=2 μg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Lipopolysaccharide (LPS)-binding

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP04282_predicted_structure.pdb to download.

DRAMP04282

• • Function

  • Antibacterial activity against Gram-negative bacteria.

• ·Literature 1

• • Title

  • Biological properties of structurally related alpha-helical cationic antimicrobial peptides.

• • Pubmed ID

  • 10085049

• • Reference

  • Infect Immun. 1999 Apr;67(4):2005-2009.

• • Author

  • Scott MG, Yan H, Hancock RE.