General Information

    • DRAMP ID

    • DRAMP04349

    • Peptide Name

    • Buf IIIb

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RVVRQWPIGRVVRRVVRRVVR

    • Sequence Length

    • 21

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04349 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04349.

Physicochemical Information

    • Formula

    • C117H209N47O23

    • Absent Amino Acids

    • ACDEFHKLMNSTY

    • Common Amino Acids

    • RV

    • Mass

    • 2642.25

    • PI

    • 12.85

    • Basic Residues

    • 8

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +8

    • Boman Index

    • -84.39

    • Hydrophobicity

    • -0.205

    • Aliphatic Index

    • 129.05

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 275

    • Polar Residues

    • 1

DRAMP04349

DRAMP04349 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Mechanism of action and specificity of antimicrobial peptides designed based on buforin IIb.

    • Reference

    • Peptides. 2012 Apr;34(2):283-289.

    • Author

    • Jang SA, Kim H, Lee JY, Shin JR, Kim da J, Cho JH, Kim SC.