• DRAMP ID

    • DRAMP04357
    • Peptide Name

    • CEME(MBI-27)
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • KWKLFKKIGIGAVLKVLTTGLIALIS
    • Sequence Length

    • 26
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Synthetic
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-
    • Target Organism

      • Gram-negative bacteria: Escherichia coli (MIC=2 μg/ml), Salmonella typhimurium (MIC=2 μg/ml), Pseudomonas aeruginosa K799 (MIC=5 μg/ml), Pseudomonas aeruginosa Z61 (MIC=4 μg/ml), Pseudomonas aeruginosa H744 (MIC=2 μg/ml), Pseudomonas aeruginosa H374 (MIC=2 μg/ml), Pseudomonas aeruginosa H547 (MIC=2 μg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Serum or Protease Type

    • Not available
    • Stability Data

    • Not available
    • Assay

    • Not available
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP04357 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP04357.
    • Formula

    • C137H236N32O30
    • Absent Amino Acids

    • CDEHMNPQRY
    • Common Amino Acids

    • KL
    • Mass

    • 2811.58
    • PI

    • 10.6
    • Basic Residues

    • 5
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 15
    • Net Charge

    • +5
    • Boman Index

    • 27.82
    • Hydrophobicity

    • 1.077
    • Aliphatic Index

    • 165
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 220
    • Polar Residues

    • 6

DRAMP04357

DRAMP04357 chydropathy plot
    • Function

    • Antibacterial activity against Gram-negative bacteria.
  • ·Literature 1
    • Title

    • Biological properties of structurally related alpha-helical cationic antimicrobial peptides.
    • Reference

    • Infect Immun. 1999 Apr;67(4):2005-2009.
    • Author

    • Scott MG, Yan H, Hancock RE.