• • DRAMP ID

  • DRAMP04362

• • Peptide Name

  • PDD-A-4 (PDD-A analog)

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • IDWKKIFEKVKDLV

• • Sequence Length

  • 14

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacterium: Escherichia coli (MIC=47.5 µM);
    • Gram-positive bacterium: Bacillus subtilis (MIC=17.5 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP04362_predicted_structure.pdb to download.

DRAMP04362

• • Function

  • Has antimicrobial activity against the Gram-positive bacterium B. subtilis and Gram-negative bacterium E. coli.

• • Chemical modification

  • C-terminal amidation.

• ·Literature 1

• • Title

  • New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs.

• • Pubmed ID

  • 18375018

• • Reference

  • Peptides. 2008 Jun;29(6):992-1003.

• • Author

  • Cerovský V, Slaninová J, Fucík V, Hulacová H, Borovicková L, Jezek R, Bednárová L.