General Information
-
DRAMP ID
- DRAMP04394
-
Peptide Name
- EP2 (Earthworm,animals)
-
Source
- Eisenia foetida (Common brandling worm)
-
Family
- Belongs to the antibacterial vermipeptides family (AVPF)
-
Gene
- Not found
-
Sequence
- AMVSS
-
Sequence Length
- 5
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
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Target Organism
-
- [Ref.European Journal of Soil Biology, 2007, 43 S127-S134] Gram-negative bacteria: Pseudomonas pyocyanea (IC=11.4 μg/ml), Acinetobacter baumanii (IC=11.4 μg/ml), Klebsiella terrigena (IC=11.4 μg/ml);
- Gram-positive bacteria: Enterococcus gallinarum (IC=11.4 μg/ml), Enterococcus faecalis (IC=22.8 μg/ml).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP04394.
Physicochemical Information
-
Formula
- C19H35N5O8S
Absent Amino Acids
- CDEFGHIKLNPQRTWY
Common Amino Acids
- S
Mass
- 493.58
PI
- 5.57
Basic Residues
- 0
Acidic Residues
- 0
Hydrophobic Residues
- 2
Net Charge
- 0
-
Boman Index
- 1.4
Hydrophobicity
- 1.26
Aliphatic Index
- 78
Half Life
-
- Mammalian:4.4 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 2
DRAMP04394
Comments Information
Function
- Antibacterial activity against Gram-negative and Gram-positive bacteria.
Literature Information
- ·Literature 1
-
Title
- A novel antimicrobial vermipeptide family from earthworm Eisenia fetida.
-
Pubmed ID
- PubMed ID is not available
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Reference
- European Journal of Soil Biology, 2007, 43:S127-S134.
-
Author
- C Wang, Z Suna, X Zhang, G Xu