• DRAMP ID

    • DRAMP04394
    • Peptide Name

    • EP2 (Earthworm,animals)
    • Source

    • Eisenia foetida (Common brandling worm)
    • Family

    • Belongs to the antibacterial vermipeptides family (AVPF)
    • Gene

    • Not found
    • Sequence

    • AMVSS
    • Sequence Length

    • 5
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • [Ref.European Journal of Soil Biology, 2007, 43 S127-S134] Gram-negative bacteria: Pseudomonas pyocyanea (IC=11.4 μg/ml), Acinetobacter baumanii (IC=11.4 μg/ml), Klebsiella terrigena (IC=11.4 μg/ml);
      • Gram-positive bacteria: Enterococcus gallinarum (IC=11.4 μg/ml), Enterococcus faecalis (IC=22.8 μg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP04394 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP04394.
    • Formula

    • C19H35N5O8S
    • Absent Amino Acids

    • CDEFGHIKLNPQRTWY
    • Common Amino Acids

    • S
    • Mass

    • 493.58
    • PI

    • 5.57
    • Basic Residues

    • 0
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 2
    • Net Charge

    • 0
    • Boman Index

    • 1.4
    • Hydrophobicity

    • 1.26
    • Aliphatic Index

    • 78
    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 2

DRAMP04394

    • Function

    • Antibacterial activity against Gram-negative and Gram-positive bacteria.
  • ·Literature 1
    • Title

    • A novel antimicrobial vermipeptide family from earthworm Eisenia fetida.
    • Reference

    • European Journal of Soil Biology, 2007, 43:S127-S134.
    • Author

    • C Wang, Z Suna, X Zhang, G Xu