General Information

    • DRAMP ID

    • DRAMP04412

    • Peptide Name

    • Defensin

    • Source

    • Mamestra brassicae (Cabbage moth)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ASCYLLDGYAAGRDDCRAHCIAPRNRRLYCASYQVCVCRY

    • Sequence Length

    • 40

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04412 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C193H300N62O56S6

    • Absent Amino Acids

    • EFKMTW

    • Common Amino Acids

    • ACR

    • Mass

    • 4577.25

    • PI

    • 8.65

    • Basic Residues

    • 7

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +4

    • Boman Index

    • -91.84

    • Hydrophobicity

    • -0.203

    • Aliphatic Index

    • 68.5

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 7825

    • Absorbance 280nm

    • 200.64

    • Polar Residues

    • 16

DRAMP04412

DRAMP04412 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Molecular characterization of a defensin in the IZD-MB-0503 cell line derived from immunocytes of the insect Mamestra brassicae (Lepidoptera).

    • Reference

    • Biol Cell. 2003 Jan-Feb;95(1):53-57.

    • Author

    • Mandrioli M, Bugli S, Saltini S, Genedani S, Ottaviani E.