General Information

    • DRAMP ID

    • DRAMP04416

    • Peptide Name

    • Defensin 3 (Def3)

    • Source

    • Triatoma brasiliensis (Blood-sucking bug)

    • Family

    • Not found

    • Gene

    • def3

    • Sequence

    • ATCDLFSFQSQWVTPNHAACAAHCLLRGNRGGECKGTICHCRK

    • Sequence Length

    • 43

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04416 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04416.

Physicochemical Information

    • Formula

    • C197H309N65O57S6

    • Absent Amino Acids

    • MY

    • Common Amino Acids

    • C

    • Mass

    • 4692.38

    • PI

    • 8.69

    • Basic Residues

    • 8

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 13

    • Net Charge

    • +6

    • Boman Index

    • -71.74

    • Hydrophobicity

    • -0.233

    • Aliphatic Index

    • 54.65

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5875

    • Absorbance 280nm

    • 139.88

    • Polar Residues

    • 17

DRAMP04416

DRAMP04416 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Two novel defensin-encoding genes of the Chagas disease vector Triatoma brasiliensis (Reduviidae, Triatominae): gene expression and peptide-structure modeling.

    • Reference

    • J Insect Physiol. 2009 Sep;55(9):840-848.

    • Author

    • Waniek PJ, Castro HC, Sathler PC, Miceli L, Jansen AM, Araújo CA.