General Information

    • DRAMP ID

    • DRAMP04422

    • Peptide Name

    • Defensin 1

    • Source

    • Stomoxys calcitrans (Stable fly) (Conops calcitrans)

    • Family

    • Not found

    • Gene

    • fbd1

    • Sequence

    • ATCDLLSGMGVNHSACAAHCVLRGNRGGYCNSKAVCVCR

    • Sequence Length

    • 39

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04422 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04422.

Physicochemical Information

    • Formula

    • C160H266N56O50S7

    • Absent Amino Acids

    • EFIPQW

    • Common Amino Acids

    • C

    • Mass

    • 3998.64

    • PI

    • 8.69

    • Basic Residues

    • 6

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +5

    • Boman Index

    • -46.48

    • Hydrophobicity

    • 0.254

    • Aliphatic Index

    • 72.56

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1865

    • Absorbance 280nm

    • 49.08

    • Polar Residues

    • 19

DRAMP04422

DRAMP04422 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Expression and regulation of the genes, smd1 and smd2, which encode midgut-specific defensin molecules in Stomoxys calcitrans.

    • Reference

    • Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases

    • Author

    • Munks R.J.L, Lehane S.M, Lehane M.J.