General Information

    • DRAMP ID

    • DRAMP04423

    • Peptide Name

    • Defensin

    • Source

    • Musca domestica (House fly)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ATCDLLSGTGVGHSACAAHCLLRGNRGGYCNGKGVCVCRN

    • Sequence Length

    • 40

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04423 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04423.

Physicochemical Information

    • Formula

    • C160H265N57O51S6

    • Absent Amino Acids

    • EFIMPQW

    • Common Amino Acids

    • G

    • Mass

    • 3995.58

    • PI

    • 8.69

    • Basic Residues

    • 6

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +5

    • Boman Index

    • -46.11

    • Hydrophobicity

    • 0.118

    • Aliphatic Index

    • 70.75

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1865

    • Absorbance 280nm

    • 47.82

    • Polar Residues

    • 22

DRAMP04423

DRAMP04423 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Cloning and sequence analysis of the full-length cDNA encoding defensin, an antimicrobial peptide from the housefly (Musca domestica).

    • Reference

    • Dong Wu Xue Bao 2003, 49:0-0.

    • Author

    • Wang LC, Wang JX, Wang LY, Zhao XF.