General Information

    • DRAMP ID

    • DRAMP04433

    • Peptide Name

    • Defensin 2

    • Source

    • Panulirus japonicus (Japanese spiny lobster)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • EPEPSYILDCRTNGGRCVTGYCSNTLPYSCGGGAICCRHAYG

    • Sequence Length

    • 42

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04433 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04433.

Physicochemical Information

    • Formula

    • C185H283N55O61S6

    • Absent Amino Acids

    • FKMQW

    • Common Amino Acids

    • G

    • Mass

    • 4445.97

    • PI

    • 6.78

    • Basic Residues

    • 4

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +1

    • Boman Index

    • -61.91

    • Hydrophobicity

    • -0.288

    • Aliphatic Index

    • 48.81

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 6335

    • Absorbance 280nm

    • 154.51

    • Polar Residues

    • 25

DRAMP04433

DRAMP04433 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Characterization of two isoforms of Japanese spiny lobster Panulirus japonicus defensin cDNA.

    • Reference

    • Dev Comp Immunol. 2009 Apr;33(4):434-438.

    • Author

    • Pisuttharachai D, Yasuike M, Aono H, Yano Y, Murakami K, Kondo H, Aoki T, Hirono I.