General Information
-
DRAMP ID
- DRAMP04436
-
Peptide Name
- Beta defensin 1 (Beta-defensin-1)
-
Source
- Equus caballus (Horse)
-
Family
- Not found
-
Gene
- defb1
-
Sequence
- FTAGIETSFSCSQNGGFCISPKCLPGSKQIGTCILPGSKCCRKK
-
Sequence Length
- 44
-
UniProt Entry
- Q865P6
-
Protein Existence
- Predicted
Activity Information
-
Biological Activity
- Antimicrobial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- Please click DRAMP04436_predicted_structure.pdb to download.
Physicochemical Information
-
Formula
- C196H321N55O59S6
Absent Amino Acids
- DHMVWY
Common Amino Acids
- CGS
Mass
- 4584.4
PI
- 9.13
Basic Residues
- 6
Acidic Residues
- 1
Hydrophobic Residues
- 10
Net Charge
- +5
-
Boman Index
- -41.72
Hydrophobicity
- -0.03
Aliphatic Index
- 55.45
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 375
Absorbance 280nm
- 8.72
Polar Residues
- 22
DRAMP04436
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Equine beta-defensin-1: full-length cDNA sequence and tissue expression.
-
Pubmed ID
- 15113660
-
Reference
- Vet Immunol Immunopathol. 2004 May;99(1-2):127-132.
-
Author
- Davis EG, Sang Y, Blecha F.