General Information

    • DRAMP ID

    • DRAMP04452

    • Peptide Name

    • Defensin protein 2

    • Source

    • Amblyomma hebraeum (bont tick)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • MATQRREISWTFGPLYTWRTTKGYGTTLETTNATSTSSKPSRRYENPYGCPTDEGKCFDRCNDSEFEGGYCGGSYRATCVCYRT

    • Sequence Length

    • 84

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04452 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C407H611N117O135S7

    • Absent Amino Acids

    • H

    • Common Amino Acids

    • T

    • Mass

    • 9527.45

    • PI

    • 8.24

    • Basic Residues

    • 11

    • Acidic Residues

    • 9

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +2

    • Boman Index

    • -232.93

    • Hydrophobicity

    • -0.982

    • Aliphatic Index

    • 20.95

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 21805

    • Absorbance 280nm

    • 262.71

    • Polar Residues

    • 46

DRAMP04452

DRAMP04452 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Two Novel Anionic Defensin-like antimicrobial proteins from Hemolymph of the Female Tick, Amblyomma hebraeum.

    • Reference

    • Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases

    • Author

    • Lai R, Turner PC, Lomas LO, Jonczy J, Rees HH.