General Information

    • DRAMP ID

    • DRAMP04490

    • Peptide Name

    • Myeloid antimicrobial peptide

    • Source

    • Ovis aries (Sheep)

    • Family

    • Not found

    • Gene

    • Map-34

    • Sequence

    • SYREAVLRAVDQFNERSAEANLYRLLELDPPPEQDAEDRGARKPVSFKVKETVCPRTSQQPVEQCD

    • Sequence Length

    • 66

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04490 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C325H519N97O108S2

    • Absent Amino Acids

    • HIMW

    • Common Amino Acids

    • ER

    • Mass

    • 7577.4

    • PI

    • 4.85

    • Basic Residues

    • 10

    • Acidic Residues

    • 13

    • Hydrophobic Residues

    • 19

    • Net Charge

    • -3

    • Boman Index

    • -210.01

    • Hydrophobicity

    • -0.982

    • Aliphatic Index

    • 65

    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 3105

    • Absorbance 280nm

    • 47.77

    • Polar Residues

    • 13

DRAMP04490

DRAMP04490 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Molecular analysis of the sheep cathelin family reveals a novel antimicrobial peptide.

    • Reference

    • FEBS Lett. 1995 Dec 27;377(3):519-522.

    • Author

    • Mahoney MM, Lee AY, Brezinski-Caliguri DJ, Huttner KM.