General Information

    • DRAMP ID

    • DRAMP04503

    • Peptide Name

    • Pelophylaxin-1 (Frogs, amphibians, animals)

    • Source

    • Pelophylax plancyi fukienensis (Fukien gold-striped pond frog)

    • Family

    • Not found

    • Gene

    • pelophylaxin-1

    • Sequence

    • GILTDTLKGAAKNVAGVLLDKLKCKITGGC

    • Sequence Length

    • 30

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04503 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C131H234N36O39S2

    • Absent Amino Acids

    • EFHMPQRSWY

    • Common Amino Acids

    • GKL

    • Mass

    • 3001.64

    • PI

    • 9.24

    • Basic Residues

    • 5

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +3

    • Boman Index

    • -4.33

    • Hydrophobicity

    • 0.423

    • Aliphatic Index

    • 120.33

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 4.31

    • Polar Residues

    • 11

DRAMP04503

DRAMP04503 chydropathy plot

Comments Information

    • Function

    • Amphibian defense peptide.

Literature Information

  • ·Literature 1

    • Title

    • Pelophylaxins: novel antimicrobial peptide homologs from the skin secretion of the Fukien gold-striped pond frog, Pelophylax plancyi fukienensis: identification by "shotgun" cDNA cloning and sequence analysis.

    • Reference

    • Peptides. 2006 Jan;27(1):36-41.

    • Author

    • Zhou M, Chen T, Walker B, Shaw C.