General Information

    • DRAMP ID

    • DRAMP04522

    • Peptide Name

    • Brevinin-2LT2 antimicrobial peptide (Frogs, amphibians, animals)

    • Source

    • Hylarana latouchii (broad-folded frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • MFTMKKSMLLLFFLGMISLSLCQDERGADEDDGGEMTEEEKRGAFGDFLKGAAKKAGLKILSIAQCKLSGTC

    • Sequence Length

    • 72

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04522 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04522.

Physicochemical Information

    • Formula

    • C340H556N88O105S8

    • Absent Amino Acids

    • HNPVWY

    • Common Amino Acids

    • LG

    • Mass

    • 7813.16

    • PI

    • 5.3

    • Basic Residues

    • 10

    • Acidic Residues

    • 11

    • Hydrophobic Residues

    • 24

    • Net Charge

    • -1

    • Boman Index

    • -80.72

    • Hydrophobicity

    • -0.029

    • Aliphatic Index

    • 78.75

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 1.76

    • Polar Residues

    • 20

DRAMP04522

DRAMP04522 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Construction of cDNA library of Hylarana latouchii skin tissue withcloning and sequence analysis of the cDNA encoding antimicrobialpeptides brevinin-2LTs.

    • Reference

    • Submitted (JAN-2009) to the EMBL/GenBank/DDBJ database

    • Author

    • Wang H, Hu Y.