General Information
-
DRAMP ID
- DRAMP04549
-
Peptide Name
- 17Hc
-
Source
- Halocynthia aurantium
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- WLNALLHHGLNCAKGVL
-
Sequence Length
- 17
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP04549.
Physicochemical Information
-
Formula
- C85H135N25O20S
Absent Amino Acids
- DEFIMPQRSTY
Common Amino Acids
- L
Mass
- 1859.22
PI
- 8.24
Basic Residues
- 3
Acidic Residues
- 0
Hydrophobic Residues
- 9
Net Charge
- +3
-
Boman Index
- 9.6
Hydrophobicity
- 0.606
Aliphatic Index
- 143.53
Half Life
-
- Mammalian:2.8 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 343.75
Polar Residues
- 5
DRAMP04549
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Biological Activities of Synthetic Analogs of Halocidin, an Antimicrobial Peptide from the Tunicate Halocynthia aurantium.
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Pubmed ID
- 12878508
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Reference
- Antimicrob Agents Chemother. 2003 Aug;47(8):2481-2486.
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Author
- Jang WS, Kim CH, Kim KN, Park SY, Lee JH, Son SM, Lee IH.