General Information

    • DRAMP ID

    • DRAMP04553

    • Peptide Name

    • H. erythraea B2RP

    • Source

    • Hylarana erythraea

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GVIKSVLKGVAKTVALGML

    • Sequence Length

    • 19

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Anti-Gram-

    • Target Organism

      • Gram-negative bacterium: Escherichia coli (MIC=12.5 microM);
      • Gram-poaitive bacteria: Staphylococcus aureus (MIC=12.5 microM), multidrug-resistant clinical isolates of Acetinobacter baumannii (MIC in the range 6-12.5 microM).
      • Yeast: Candida albicans (MIC=50 microM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04553 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C86H158N22O22S

    • Absent Amino Acids

    • CDEFHNPQRWY

    • Common Amino Acids

    • V

    • Mass

    • 1884.39

    • PI

    • 10.3

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +3

    • Boman Index

    • 22.01

    • Hydrophobicity

    • 1.253

    • Aliphatic Index

    • 153.68

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP04553

DRAMP04553 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial peptides from the skin secretions of the South-East Asian frog Hylarana erythraea (Ranidae).

    • Reference

    • Peptides. 2010 Apr;31(4):548-554.

    • Author

    • Al-Ghaferi N, Kolodziejek J, Nowotny N, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD, Conlon JM.