General Information

    • DRAMP ID

    • DRAMP04564

    • Peptide Name

    • Epinecidin-1 (Epi-1; fish, animals)

    • Source

    • Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FIFHIIKGLFHAGKMIHGLVTRRRH

    • Sequence Length

    • 25

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04564 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04564.

Physicochemical Information

    • Formula

    • C140H222N44O27S

    • Absent Amino Acids

    • CDENPQSWY

    • Common Amino Acids

    • HI

    • Mass

    • 2985.64

    • PI

    • 12.31

    • Basic Residues

    • 9

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +9

    • Boman Index

    • -27.59

    • Hydrophobicity

    • 0.236

    • Aliphatic Index

    • 109.2

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP04564

DRAMP04564 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Gene expression and localization of the epinecidin-1 antimicrobial peptide in the grouper (Epinephelus coioides), and its role in protecting fish against pathogenic infection.

    • Reference

    • DNA Cell Biol. 2007 Jun;26(6):403-413.

    • Author

    • Pan CY, Chen JY, Cheng YS, Chen CY, Ni IH, Sheen JF, Pan YL, Kuo CM.