General Information

    • DRAMP ID

    • DRAMP04576

    • Peptide Name

    • Cg-Prp

    • Source

    • Crassostrea gigas

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ILENLLARSTNEDREGSIFDTGPIRRPKPRPRPRPEG

    • Sequence Length

    • 37

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04576 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04576.

Physicochemical Information

    • Formula

    • C182H303N61O56

    • Absent Amino Acids

    • CHMQVWY

    • Common Amino Acids

    • R

    • Mass

    • 4241.78

    • PI

    • 10.53

    • Basic Residues

    • 8

    • Acidic Residues

    • 6

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +2

    • Boman Index

    • -142.76

    • Hydrophobicity

    • -1.289

    • Aliphatic Index

    • 65.95

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 9

DRAMP04576

DRAMP04576 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Oyster hemocytes express a proline-rich peptide displaying synergistic antimicrobial activity with a defensin.

    • Reference

    • Mol Immunol. 2009 Feb;46(4):516-522.

    • Author

    • Gueguen Y, Bernard R, Julie F, Paulina S, Delphine DG, Franck V, Philippe B, Evelyne B.