General Information

    • DRAMP ID

    • DRAMP04579

    • Peptide Name

    • ECATH-2

    • Source

    • Equus asinus

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • KRRHWFPLSFQEFLEQLRRFRDQLPFP

    • Sequence Length

    • 27

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04579 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C169H249N49O38

    • Absent Amino Acids

    • ACGIMNTVY

    • Common Amino Acids

    • FR

    • Mass

    • 3575.14

    • PI

    • 11.42

    • Basic Residues

    • 7

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +4

    • Boman Index

    • -90.26

    • Hydrophobicity

    • -1.033

    • Aliphatic Index

    • 57.78

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 211.54

    • Polar Residues

    • 1

DRAMP04579

DRAMP04579 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Novel cathelicidins in horse leukocytes(1).

    • Reference

    • FEBS Lett. 1999 Sep 3;457(3):459-464.

    • Author

    • Scocchi M, Bontempo D, Boscolo S, Tomasinsig L, Giulotto E, Zanetti M.