General Information
-
DRAMP ID
- DRAMP04584
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Peptide Name
- SpStrongylocin 1 (S. purpuratus Strongylocin, sea urchin, Echinoidea, animals)
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Source
- Strongylocentrotus purpuratus
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Family
- Not found
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Gene
- Not found
-
Sequence
- IFNSIYHRKCVVKNRCETVSGHKTCKDLTCCRAVIFRHERPEVCRPST
-
Sequence Length
- 48
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UniProt Entry
- No entry found
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Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal, Antiviral
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP04584.
Physicochemical Information
-
Formula
- C239H392N78O67S6
Absent Amino Acids
- MQW
Common Amino Acids
- CR
Mass
- 5622.58
PI
- 9.34
Basic Residues
- 13
Acidic Residues
- 4
Hydrophobic Residues
- 12
Net Charge
- +9
-
Boman Index
- -132.48
Hydrophobicity
- -0.471
Aliphatic Index
- 64.79
Half Life
-
- Mammalian:20 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 1865
Absorbance 280nm
- 39.68
Polar Residues
- 17
DRAMP04584
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Two recombinant peptides, SpStrongylocins 1 and 2, from Strongylocentrotus purpuratus, show antimicrobial activity against Gram-positive and Gram-negative bacteria.
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Pubmed ID
- 19852980
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Reference
- Dev Comp Immunol. 2010 Mar;34(3):286-292.
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Author
- Li C, Blencke HM, Smith LC, Karp MT, Stensvåg K.