General Information

    • DRAMP ID

    • DRAMP04613

    • Peptide Name

    • HV-BBI(3-18) (X)

    • Source

    • Odorrana grahami

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • IGCWTKSIPPRPCFVK

    • Sequence Length

    • 16

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04613 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04613.

Physicochemical Information

    • Formula

    • C85H134N22O19S2

    • Absent Amino Acids

    • ADEHLMNQY

    • Common Amino Acids

    • P

    • Mass

    • 1832.26

    • PI

    • 9.5

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +3

    • Boman Index

    • -9.3

    • Hydrophobicity

    • 0.069

    • Aliphatic Index

    • 66.88

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5625

    • Absorbance 280nm

    • 375

    • Polar Residues

    • 5

DRAMP04613

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Inhibitory and antimicrobial activities of OGTI and HV-BBI peptides, fragments and analogs derived from amphibian skin.

    • Reference

    • Peptides. 2012 Jun;35(2):276-284.

    • Author

    • Dębowski D, Łukajtis R, Łęgowska A, Karna N, Pikuła M, Wysocka M, Maliszewska I, Sieńczyk M, Lesner A, Rolka K.