General Information

    • DRAMP ID

    • DRAMP04614

    • Peptide Name

    • [Ser14,Ile15]OGTI (II)

    • Source

    • Odorrana grahami

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • AVNIPFKVHFRCKSIFC

    • Sequence Length

    • 17

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04614 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04614.

Physicochemical Information

    • Formula

    • C94H145N25O20S2

    • Absent Amino Acids

    • DEGLMQTWY

    • Common Amino Acids

    • F

    • Mass

    • 2009.46

    • PI

    • 9.51

    • Basic Residues

    • 4

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +4

    • Boman Index

    • -9.49

    • Hydrophobicity

    • 0.659

    • Aliphatic Index

    • 85.88

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 7.81

    • Polar Residues

    • 4

DRAMP04614

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Inhibitory and antimicrobial activities of OGTI and HV-BBI peptides, fragments and analogs derived from amphibian skin.

    • Reference

    • Peptides. 2012 Jun;35(2):276-284.

    • Author

    • Dębowski D, Łukajtis R, Łęgowska A, Karna N, Pikuła M, Wysocka M, Maliszewska I, Sieńczyk M, Lesner A, Rolka K.